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China Peanut Skin Extract Proanthocyanidin 95% - Antioxidant Suppliers and Factory Direct Offer
Bioactive Composition
Proanthocyanidins (OPCs)
Constitute 60–95% of Peanut Skin Extract, acting as powerful antioxidants that neutralize free radicals and reduce oxidative stress.
Polyphenols & Flavonoids
Including catechins and epicatechins, which enhance anti-inflammatory and antimicrobial effects.
Vitamins & Minerals
Vitamin E (tocopherols), zinc, and magnesium contribute to skin barrier repair and UV protection.
Mechanisms of Action
1. Antioxidant Activity
- Free Radical Scavenging: OPCs donate electrons to unstable free radicals (e.g., ROS), preventing cellular DNA and lipid damage.
- Enzyme Modulation: Suppresses xanthine oxidase (XOD) activity, reducing uric acid production and mitigating gout or kidney injury.
2. Anti-Inflammatory Pathways
- Cytokine Inhibition: Downregulates pro-inflammatory markers (IL-1β, TNF-α) and inhibits NLRP3 inflammasome activation, curbing chronic inflammation.
- Endoplasmic Reticulum Stress (ERS) Regulation: Alleviates ERS-induced apoptosis in renal cells, protecting against metabolic stress.
Health Benefits
Renal Protection
- Kidney Injury Mitigation: In rat studies, PSE (200 mg/kg/day) reduced serum creatinine, urea nitrogen, and uric acid by 30–40% in high-fat-diet models, preventing renal tubular degeneration.
- Antifibrotic Effects: Suppresses collagen deposition and fibrotic pathways in renal tissues.
Metabolic Health
- Lipid Regulation: Lowers LDL oxidation and triglycerides, reducing risks of atherosclerosis.
- Hyperglycemia Control: Enhances insulin sensitivity and glucose uptake in adipose tissues.
Dermatological Benefits
- Anti-Aging: Vitamin E and OPCs inhibit MMP enzymes, preserving collagen and reducing wrinkles.
- Acne Management: Zinc and magnesium reduce P. acnes proliferation and sebum overproduction.
- Hyperpigmentation Correction: Vitamin C blocks tyrosinase activity, lightening dark spots and improving skin tone uniformity.
Functions & Applications
Key Functions
- Food Industry: Natural antioxidant for meat/fat preservation; colorant (red pigment); functional ingredient in beverages/supplements.
- Health Supplements: Used in capsules/extracts for vascular health, antioxidant support, and blood circulation.
- Biomedical Research: Investigated for diabetes management, neuroprotection, and chemoprevention.
Applications
- Health Supplement, Nutritional supplements.
- Capsule, Softgel, Tablet and subcontract.
- Beverages, Solid Beverages, Food Additives.
Production Flow Chart
Product Name
Peanut Skin Extract
Botanical Name
Arachis hypogaea
Part Used
Skin
Extraction Solvent
Ethanol / Water
Frequently Asked Questions
What are the primary active ingredients in Peanut Skin Extract?
Peanut Skin Extract is highly concentrated with bioactive compounds, primarily Proanthocyanidins (OPCs) constituting 60–95%, alongside polyphenols, flavonoids (like catechins and epicatechins), and essential vitamins and minerals like Vitamin E, zinc, and magnesium.
How does Peanut Skin Extract support kidney health?
It mitigates kidney damage by reducing key markers such as serum creatinine, urea nitrogen, and uric acid. Additionally, it offers antifibrotic benefits by suppressing collagen deposition and protecting renal cells against endoplasmic reticulum stress.
Can Peanut Skin Extract improve skin health and appearance?
Yes. The extract provides anti-aging benefits by preserving collagen, aids in acne management by regulating sebum production, and helps correct hyperpigmentation by blocking tyrosinase activity to promote a more even skin tone.
What are the main commercial applications of Peanut Skin Extract?
It is widely used in the food industry as a natural antioxidant and colorant, in the health supplement sector for capsules and tablets targeting vascular health, and in biomedical research for metabolic and cellular health studies.
What solvents are used to manufacture this extract?
According to the production standard, the extraction process utilizes a clean mixture of Ethanol and Water to safely isolate the active phytochemicals from the peanut skins.