Hot Products
China Suppliers Factory Proanthocyanidin 95% Peanut Skin Extract – Powerful Antioxidant Polyphenol
Bioactive Composition
Proanthocyanidins (OPCs)
Constitute 60–95% of Peanut Skin Extract, acting as powerful antioxidants that neutralize free radicals and reduce oxidative stress.
Polyphenols & Flavonoids
Including catechins and epicatechins, which enhance anti-inflammatory and antimicrobial effects.
Vitamins & Minerals
Vitamin E (tocopherols), zinc, and magnesium contribute to skin barrier repair and UV protection.
Mechanisms of Action
1. Antioxidant Activity
A: Free Radical Scavenging: OPCs donate electrons to unstable free radicals (e.g., ROS), preventing cellular DNA and lipid damage.
B: Enzyme Modulation: Suppresses xanthine oxidase (XOD) activity, reducing uric acid production and mitigating gout or kidney injury.
B: Enzyme Modulation: Suppresses xanthine oxidase (XOD) activity, reducing uric acid production and mitigating gout or kidney injury.
2. Anti-Inflammatory Pathways
A: Cytokine Inhibition: Downregulates pro-inflammatory markers (IL-1β, TNF-α) and inhibits NLRP3 inflammasome activation, curbing chronic inflammation.
B: Endoplasmic Reticulum Stress (ERS) Regulation: Alleviates ERS-induced apoptosis in renal cells, protecting against metabolic stress.
B: Endoplasmic Reticulum Stress (ERS) Regulation: Alleviates ERS-induced apoptosis in renal cells, protecting against metabolic stress.
Health Benefits
1. Renal Protection
A: Kidney Injury Mitigation: In rat studies, PSE (200 mg/kg/day) reduced serum creatinine, urea nitrogen, and uric acid by 30–40% in high-fat-diet models, preventing renal tubular degeneration.
B: Antifibrotic Effects: Suppresses collagen deposition and fibrotic pathways in renal tissues.
B: Antifibrotic Effects: Suppresses collagen deposition and fibrotic pathways in renal tissues.
2. Metabolic Health
A: Lipid Regulation: Lowers LDL oxidation and triglycerides, reducing risks of atherosclerosis.
B: Hyperglycemia Control: Enhances insulin sensitivity and glucose uptake in adipose tissues.
B: Hyperglycemia Control: Enhances insulin sensitivity and glucose uptake in adipose tissues.
3. Dermatological Benefits
A: Anti-Aging: Vitamin E and OPCs inhibit MMP enzymes, preserving collagen and reducing wrinkles.
B: Acne Management: Zinc and magnesium reduce P. acnes proliferation and sebum overproduction.
C: Hyperpigmentation Correction: Vitamin C blocks tyrosinase activity, lightening dark spots and improving skin tone uniformity.
B: Acne Management: Zinc and magnesium reduce P. acnes proliferation and sebum overproduction.
C: Hyperpigmentation Correction: Vitamin C blocks tyrosinase activity, lightening dark spots and improving skin tone uniformity.
Functions & Applications
1. Food Industry
Natural antioxidant for meat/fat preservation; colorant (red pigment); functional ingredient in beverages/supplements.
2. Health Supplements
Used in capsules/extracts for vascular health, antioxidant support, and blood circulation.
3. Biomedical Research
Investigated for diabetes management, neuroprotection, and chemoprevention.
Applications:
• Health Supplement, Nutritional supplements.
• Capsule, Softgel, Tablet and subcontract.
• Beverages, Solid Beverages, Food Additives.
• Capsule, Softgel, Tablet and subcontract.
• Beverages, Solid Beverages, Food Additives.
Production Flow Chart
Frequently Asked Questions
What are the primary active components in Peanut Skin Extract?
Peanut Skin Extract is highly concentrated with bioactive phytochemicals, primarily consisting of 60–95% Proanthocyanidins (OPCs), along with polyphenols, flavonoids (such as catechins and epicatechins), and essential vitamins and minerals like Vitamin E, zinc, and magnesium.
How does Peanut Skin Extract benefit kidney health?
It provides renal protection by mitigating kidney injury and suppressing fibrotic pathways. Studies indicate it can significantly reduce serum creatinine, urea nitrogen, and uric acid, preventing renal tubular degeneration and collagen deposition in renal tissues.
What dermatological benefits does the extract offer?
Peanut Skin Extract offers anti-aging benefits by inhibiting MMP enzymes to preserve collagen, manages acne by reducing sebum overproduction and P. acnes proliferation, and helps correct hyperpigmentation by blocking tyrosinase activity to lighten dark spots.
What industries commonly utilize Peanut Skin Extract?
It is widely used in the food industry as a natural antioxidant and red pigment colorant, in the health supplement sector for vascular and antioxidant support capsules, and in biomedical research for diabetes management and neuroprotection studies.
What solvents are used in the manufacturing process of this extract?
The extraction process utilizes a safe and efficient solvent mixture of Ethanol and Water to isolate the active compounds from the skin of the Arachis hypogaea plant.