Peanut Skin Extract Proanthocyanidin 95% Anti Oxidant
Bioactive Composition
1, Proanthocyanidins (OPCs): Constitute 60–95% of Peanut Skin Extract , acting as powerful antioxidants that neutralize free radicals and reduce oxidative stress
2,Polyphenols&Flavonoids: Including catechins and epicatechins, which enhance anti-inflammatory and antimicrobial effects .
3, Vitamins & Minerals: Vitamin E (tocopherols), zinc, and magnesium contribute to skin barrier repair and UV protection
Mechanisms of Action
A: Free Radical Scavenging: OPCs donate electrons to unstable free radicals (e.g., ROS), preventing cellular DNA and lipid damage
B: Enzyme Modulation: Suppresses xanthine oxidase (XOD) activity, reducing uric acid production and mitigating gout or kidney injury
2. Anti-Inflammatory Pathways
A: Cytokine Inhibition: Downregulates pro-inflammatory markers (IL-1β, TNF-α) and inhibits NLRP3 inflammasome activation, curbing chronic inflammation
B: Endoplasmic Reticulum Stress (ERS) Regulation: Alleviates ERS-induced apoptosis in renal cells, protecting against metabolic stress
Health Benefits
A: Kidney Injury Mitigation: In rat studies, PSE (200 mg/kg/day) reduced serum creatinine, urea nitrogen, and uric acid by 30–40% in high-fat-diet models, preventing renal tubular degeneration
B: Antifibrotic Effects: Suppresses collagen deposition and fibrotic pathways in renal tissues
2. Metabolic Health
A, Lipid Regulation: Lowers LDL oxidation and triglycerides, reducing risks of atherosclerosis
B, Hyperglycemia Control: Enhances insulin sensitivity and glucose uptake in adipose tissues
3, Dermatological Benefits
A, Anti-Aging: Vitamin E and OPCs inhibit MMP enzymes, preserving collagen and reducing wrinkles
B, Acne Management: Zinc and magnesium reduce P. acnes proliferation and sebum overproduction
C, Hyperpigmentation Correction: Vitamin C blocks tyrosinase activity, lightening dark spots and improving skin tone uniformity
Functions
Natural antioxidant for meat/fat preservation; colorant (red pigment); functional ingredient in beverages/supplements.
2 Health Supplements:
Used in capsules/extracts for vascular health, antioxidant support, and blood circulation.
3, Biomedical Research:
Investigated for diabetes management, neuroprotection, and chemoprevention
Application:
1,Health Supplement，Nutritional supplements.
2,Capsule, Softgel, Tablet and subcontract.
3,Beverages, Solid Beverages, Food Additives.
Production Flow Chart
Botanical name: Arachis hypogaea
Part: Skin
Solvent: Ethanol/Water
Certificate of Analysis
|
Product Name |
Peanut Skin Extract |
Batch No |
20250526 |
Mfg. Date |
2025/05/26 |
||
|
Part Used |
Peanut Skin |
Batch Quantity |
2000kgs |
Exp.Date |
2026/05/25 |
||
|
ITEMS |
SPECIFICATIONS |
TEST RESULTS |
TEST METHOD |
||||
|
Appearance |
Brown Red powder |
Complies |
Visual |
||||
|
Odor |
Light Smell |
Complies |
Organoleptic |
||||
|
Taste |
Astringent |
Complies |
Organoleptic |
||||
|
Proanthocyanidins |
≥95% |
101.50% |
UV (SW/T 1-2015) |
||||
|
Sieve Size |
100% through 80 mesh |
Complies |
Sieves (CP2010-IX E) |
||||
|
Tap Density g/ml |
0.3-0.6g/ml |
0.45 |
USP36-616 |
||||
|
Bulk Density g/ml |
0.2-0.3g/ml |
0.27 |
USP36-616 |
||||
|
Loss on drying |
≤5.0% |
3.90% |
USP <731> |
||||
|
Ash |
≤3.0% |
0.60% |
USP <281> |
||||
|
Heavy Metals |
≤10 ppm |
Complies |
ICP-MS |
||||
|
As |
≤2 ppm |
Complies |
ICP-MS |
||||
|
Pb |
≤2 ppm |
Complies |
ICP-MS |
||||
|
Microbial test |
|
||||||
|
Total Plate Count |
≤1000cfu/g |
Complies |
AOAC |
||||
|
Yeast & Mold |
≤100cfu/g |
Complies |
AOAC |
||||
|
E.Coli |
≤30 MPN/100g |
Complies |
AOAC |
||||
|
Salmonella |
Negative |
Negative |
AOAC |
||||
|
Storage: Store in a well-closed container away from moisture and high temperature |
|||||||
|
Shelf life: one years when properly stored. |
|||||||
|
Conclusion: Sample quality test complies |
|||||||